In Notch, One ANK Repeat Is Not Like the Other

Filoviruses: One of These Things is (not) Like the Other

The family Filoviridae contains several of the most deadly pathogens known to date and the current Ebola virus disease (EVD) outbreak in Western Africa, due to Ebola virus (EBOV) infection, highlights the need for active and broad research into filovirus pathogenesis. However, in comparison, the seven other known filovirus family members are significantly understudied. Many of these, including ...

One protoplast is not the other!

4 One protoplast is not the other !

One ROCK is not like another

One ROCK is not like another he mammalian rho kinases, ROCKI and ROCKII, control distinct cytoskeletal functions from distinct locations, report Yoneda et al. on page 443. ROCKI is required for formation of actin stress fibers and cell adhesion, whereas ROCKII is needed for phagocytosis. The ROCK proteins are major effectors of the Rho signaling pathway, controlling cell adhesion, motility, and...

Scientific Correspondence One Protoplast Is Not the Other!

Plant protoplasts are often used as experimental material without paying attention to the tissue they are isolated from (a protoplast is a protoplast), whereas in other cases, they are considered not sufficiently able to reproduce the in planta situation. Here, we show that protoplasts are a very reliable experimental system, as long as we carefully chose their source. Transient transformation ...